2025
Bacteria as Living Biosensors for DNA
Katherine O’Connor, Paige Steppe, Daniel Worthley, Jeff Hasty, Robert Cooper Nature Reviews Bioengineering (2025)
Metatranscriptomics Uncovers Diurnal Functional Shifts in Bacterial Transgenes with Profound Metabolic Effects
Stephany Flores Ramos, Nicole Siguenza, Wuling Zhong, Ipsita Mohanty, Amulya Lingaraju, R Alexander Richter, Smruthi Karthikeyan, April L Lukowski, Qiyun Zhu, Wilhan DG Nunes, Jasmine Zemlin, Zhenjiang Zech Xu, Jeff Hasty, Pieter C Dorrestein, Satchidananda Panda, Rob Knight, Amir Zarrinpar Cell Host & Microbe (2025)

Host Evolution Improves Genetic Circuit Function in Complex Growth Environments
Joanna T Zhang, Andrew Lezia, Philip Emmanuele, Muyao Wu, Elina C Olson, Aayush Somani, Adam M Feist, Jeff Hasty

SARS-CoV-2 Infectivity Can Be Modulated Through Bacterial Grooming of the Glycocalyx
Cameron Martino, Benjamin P Kellman, Daniel R Sandoval, Thomas Mandel Clausen, Robert Cooper, Alhosna Benjdia, Feryel Soualmia, Alex E Clark, Aaron F Garretson, Clarisse A Marotz, Se Jin Song, Stephen Wandro, Livia S Zaramela, Rodolfo A Salido, Qiyun Zhu, Erick Armingol, Yoshiki Vázquez-Baeza, Daniel McDonald, James T Sorrentino, Bryn Taylor, Pedro Belda-Ferre, Promi Das, Farhana Ali, Chenguang Liang, Yujie Zhang, Luca Schifanella, Alice Covizzi, Alessia Lai, Agostino Riva, Christopher Basting, Courtney Ann Broedlow, Aki S Havulinna, Pekka Jousilahti, Mehrbod Estaki, Tomasz Kosciolek, Rayus Kuplicki, Teresa A Victor, Martin P Paulus, Kristen E Savage, Jennifer L Benbow, Emma S Spielfogel, Cheryl AM Anderson, Maria Elena Martinez, James V Lacey Jr, Shi Huang, Niina Haiminen, Laxmi Parida, Ho-Cheol Kim, Jack A Gilbert, Daniel A Sweeney, Sarah M Allard, Austin D Swafford, Susan Cheng, Michael Inouye, Teemu Niiranen, Mohit Jain, Veikko Salomaa, Karsten Zengler, Nichole R Klatt, Jeff Hasty, Olivier Berteau, Aaron F Carlin, Jeffrey D Esko, Nathan E Lewis, Rob Knight
2024
![]() Towards Understanding Tumour Colonisation by Probiotic Bacterium E. coli Nissle 1917Georgette A Radford, Laura Vrbanac, Rebekah T de Nys, Daniel L Worthley, Josephine A Wright, Jeff Hasty, Susan L Woods |
![]() Enhanced cellular longevity arising from environmental fluctuationsYuting Liu, Zhen Zhou, Hetian Su, Songlin Wu, Gavin Ni, Alex Zhang, Lev S Tsimring, Jeff Hasty, Nan Hao |
![]() Engineering plasmid copy number heterogeneity for dynamic microbial adaptationShalni Kumar, Andrew Lezia, Jeff Hasty |
![]() Live bacterial therapeutics for detection and treatment of colorectal cancerJoanna Zhang, Jeff Hasty, Amir Zarrinpar |
![]() Engineered bacterial therapeutics for detecting and treating CRCNicole Siguenza, Arianna Brevi, Joanna T Zhang, Arman Pabani, Abhinav Bhushan, Moumita Das, Yousong Ding, Jeff Hasty, Pradipta Ghosh, Amir Zarrinpar |
![]() Phenotypic Patterning through Copy Number Adaptation to Environmental GradientsPaige Steppe, Camilo Rey-Bedón, Shalni Kumar, Emerald Forrest, Niklas Van Der Wagt, Arnav Tayal, Lev Tsimring, Jeff Hasty |
2023
![]() A Standardized Set of MoClo-Compatible Inducible Promoter Systems for Tunable Gene Expression in YeastRichard O’Laughlin, Quoc Tran, Andrew Lezia, Wasu Ngamkanjanarat, Philip Emmanuele, Nan Hao, Jeff Hasty |
![]() Design of synthetic bacterial biosensorsAlyssa J Chiang, Jeff Hasty |
![]() High-resolution temporal profiling of E. coliArianna Miano, Kevin Rychel, Andrew Lezia, Anand Sastry, Bernhard Palsson, Jeff Hasty |
![]() A Microfluidic Platform for Screening Gene Expression Dynamics across Yeast Strain LibrariesElizabeth Stasiowski, Richard O’Laughlin, Shayna Holness, Nicholas Csicsery, Jeff Hasty, Nan HaoBio-protocol 13 (2023) |
![]() Engineered bacteria detect tumor DNARobert M. Cooper†, Josephine A. Wright†, Jia Q. Ng, Jarrad M. Goyne, Suzuki, Young K. Lee, Mari Ichinose, Georgette Radford, Feargal J. Ryan, Shalni Kumar, Elaine M. Thomas, Laura Vrbanac, Rob Knight, Susan L. Woods, Daniel L. Worthley, Jeff Hasty |
![]() Fabrication of Microfluidic Devices for Continuously Monitoring Yeast AgingRichard O’Laughlin, Emerald Forrest, Jeff Hasty, Nan Hao |
![]() Divergent metabolic programmes control two populations of MAIT cells that protect the lungThomas Riffelmacher, Mallory Paynich Murray, Chantal Wientjens, Shilpi Chandra, Viankail Cedillo-Castelán, Ting-Fang Chou, Sara McArdle, Christopher Dillingham, Jordan Devereaux, Aaron Nilsen, Simon Brunel, David M Lewinsohn, Jeff Hasty, Gregory Seumois, Christopher A Benedict, Pandurangan Vijayanand, Mitchell Kronenberg |
![]() Engineering longevity—design of a synthetic gene oscillator to slow cellular agingZhen Zhou, Yuting Liu, Yushen Feng, Stephen Klepin, Lev S Tsimring, Lorraine Pillus, Jeff Hasty, and Nan Hao |
![]() Stability, robustness, and containment: preparing synthetic biology for real-world deploymentShalni Kumar and Jeff Hasty |
2022
Age-dependent aggregation of ribosomal RNA-binding proteins links deterioration in chromatin stability with challenges to proteostasisJulie Paxman, Zhen Zhou, Richard O’Laughlin, Yuting Liu, Yang Li, Wanying Tian, Hetian Su, Yanfei Jiang, Shayna E Holness, Elizabeth Stasiowski, Lev S Tsimring, Lorraine Pillus, Jeff Hasty, and Nan Hao |
![]() Nutrient Gradients Mediate Complex Colony-Level Antibiotic Responses in Structured Microbial PopulationsMirjana Stevanovic, Thomas Boukéké-Lesplulier, Lukas Hupe, Jeff Hasty, Philip Bittihn, Daniel Schultz |
![]() Intestinal transgene delivery with native E. coli chassis allows persistent physiological changesBaylee J Russell, Steven D Brown, Nicole Siguenza, Irene Mai, Anand R Saran, Amulya Lingaraju, Erica S Maissy, Ana C Dantas Machado, Antonio F M Pinto, Concepcion Sanchez, Leigh-Ana Rossitto, Yukiko Miyamoto, R Alexander Richter, Samuel B Ho, Lars Eckmann, Jeff Hasty, David J Gonzalez, Alan Saghatelian, Rob Knight, Amir Zarrinpar |
![]() Design, mutate, screen: Multiplexed creation and arrayed screening of synchronized genetic clocksAndrew Lezia, Nicholas Csicsery, and Jeff Hasty Supplement 2 Supplement 3 |
2021
![]() The microbiome and human cancerGregory D. Sepich-Poore, Laurence Zitvogel, Ravid Straussman, Jeff Hasty, Jennifer A. Wargo, and Rob Knight |
![]() Rapid Assembly of Multiplex Natural CRISPR ArraysRobert M. Cooper and Jeff Hasty |
![]() Synthetic Gene Circuits: Design, Implement, and ApplyAndrew Lezia, Ariana Miano, and Jeff Hasty |
![]() Rapid, Affordable, and Uncomplicated Production of Bacterial Cell-free LysateRobert M. Cooper, Taishi Tonooka, Andriy Didovyk, and Jeff Hasty |
![]() The balance of stromal BMP signaling mediated by GREM1 and ISLR drives colorectal carcinogenesisHiroki Kobayashi, Krystyna A. Gieniec, Josephine A. Wright, Tongtong Wang, Naoya Asai, Yasuyuki Mizutani, Tadashi Ida, Ryota Ando, Nobumi Suzuki, Tamsin RM. Lannagan, Jia Q. Ng, Akitoshi Hara, Yukihiro Shiraki, Shinji Mii, Mari Ichinose, Laura Vrbanac, Matthew J. Lawrence, Tarik Sammour, Kay Uehara, Gareth Davies, Leszek Lisowski, Ian E. Alexander, Yoku Hayakawa, Lisa M. Butler, Andrew C.W. Zannettino, M. Omar Din, Jeff Hasty, Alastair D. Burt, Simon J. Leedham, Anil K. Rustgi, Siddhartha Mukherjee, Timothy C. Wang, Atsushi Enomoto, Masahide Takahashi, Daniel L. Worthley, and Susan L. Woods |
2020
![]() Survival of the weakest in non-transitive asymmetric interactionsMichael J. Liao, Arianna Miano, Chloe B. Nguyen, Lin Chao, and Jeff Hasty |
![]() A programmable fate decision landscape underlies single-cell aging in yeastYang Li, Yanfei Jiang, Julie Paxman, Richard O’Laughlin, Stephen Klepin, Yuelian Zhu, Lorraine Pillus, Lev S. Tsimring, Jeff Hasty, and Nan Hao |
![]() Interfacing gene circuits with microelectronis through engineered population dynamicsM. Omar Din, Aida Martin, Ivan Razinkov, Nicholas Csicsery, and Jeff Hasty |
![]() One-Day Construction of Multiplex Arrays to Harness Natural CRISPR-Cas SystemsRobert M. Cooper and Jeff Hasty |
![]() Inducible cell-to-cell signaling for tunable dynamics in microbial communitiesArianna Miano, Michael J. Liao and Jeff Hasty |
![]() Genome-scale transcriptional dynamics and environmental biosensingGarrett Graham, Nicholas Csicsery, Elizabeth Stasiowski, Gregoire Thouvenin, William H. Mather, Michael Ferry, Scott Cookson and Jeff Hasty |
Flower-like patterns in multi-species bacterial coloniesLiyang Xiong, Yuansheng Cao, Robert Cooper, Wouter-Jan Rappel, Jeff Hasty, and Lev S. Tsimring |
![]() Genetically engineered control of phenotypic structure in microbial coloniesPhilip Bittihn, Andriy Didovyk, Lev S. Tsimring & Jeff Hasty |
2019
![]() Advances in quantitative biology methods for studying replicative aging in Saccharomyces cerevisiaeRichard O’Laughlin, Meng Jin, Yang Li, Lorraine Pillus, Lev S. Tsimring, Jeff Hasty and Nan Hao |
![]() Rock-paper-scissors: Engineered population dynamics increase genetic stabilityMichael J. Liao, Omar Din, Lev S. Tsimring and Jeff Hasty |
![]() Divergent Aging of Isogenic Yeast Cells Revealed through Single-Cell Phenotypic DynamicsMeng Jin, Yang Li, Richard O’Laughlin, Philip Bittihn, Lorraine Pillus, Lev S. Tsimring, Jeff Hasty, and Nan Hao |
2018
![]() Flavin-based metabolic cycles are integral features of growth and division in single yeast cellsBridget L. Baumgartner, Richard O’Laughlin, Meng Jin, Lev S. Tsimring, Nan Hao and Jeff Hasty |
![]() Rational engineering of synthetic microbial systems: from single cells to consortiaPhilip Bittihn, M. Omar Din, Lev S. Tsimring, and Jeff Hasty |
![]() Microfluidics-Based Analysis of Contact-dependent Bacterial InteractionsRobert Cooper, Lev S. Tsimring, and Jeff Hasty |
![]() Coexistence and Pattern Formation in Bacterial Mixtures with Contact-Dependent KillingLiyang Xiong, Robert Cooper, and Lev S. Tsimring |
![]() Effective pressure and cell area distribution in a confined monolayerEvgeniy Khain and Lev S. Tsimring |
2017
![]() Inter-Species Population Dynamics Enhance Microbial Horizontal Gene Transfer And Spread Of Antibiotic ResistanceRobert Cooper, Lev Tsimring and Jeff Hasty |
![]() Multigenerational silencing dynamics control cell agingYang Li, Meng Jin, Richard O’Laughlin, Philip Bittihn, Lev Tsimring, Lorraine Pillus, Jeff Hasty, and Nan Hao |
![]() Rapid and Scalable Preparation of Bacterial Lysates for Cell-Free Gene ExpressionAndriy Didovyk, Taishi Tonooka, Lev Tsimring, and Jeff Hasty |
![]() Synchronized DNA cycling across a bacterial populationLeo Baumgart, William Mather, Jeff Hasty |
![]() A stabilized microbial ecosystem of self-limiting bacteria using synthetic quorum-regulated lysisSpencer R. Scott, M. Omar Din, Philip Bittihn, Liyang Xiong, Lev S. Tsimring and Jeff Hasty |
![]() Suppression of Beneficial Mutations in Dynamic Microbial PopulationsPhilip Bittihn, Jeff Hasty, and Lev S. Tsimring |
2016
![]() Synchronized cycles of bacterial lysis for in vivo deliveryM. Omar Din, Tal Danino, Arthur Prindle, Matt Skalak, Jangir Selimkhanov, Kaitlin Allen, Ellixis Julio, Eta Atolia, Lev S. Tsimring, Sangeeta N. Bhatia, Jeff Hasty |
![]() Quorum Sensing Communication Modules for Microbial ConsortiaSpencer R. Scott and Jeff Hasty |
![]() Transcriptional regulation with CRISPR-Cas9: principles, advances, and applicationsAndriy Didovyk, Bartlomiej Borek, Jeff Hasty, Lev TsimringCurrent Opinion in Biotechnology, 40:177-184 (2016) |
![]() Criticality and Adaptivity in Enzymatic NetworksPaul J. Steiner, Ruth J. Williams, Jeff Hasty, and Lev S. Tsmimring |
![]() Turing Patterning Using Gene Circuits with Gas-Induced Degradation of Quorum Sensing MoleculesBartlomiej Borek, Jeff Hasty, Lev Tsimring |
![]() FBB: A Fast Bayesian Bound tool to calibrate RNA-seq alignersIrene Rodriguez-Lujan, Jeff Hasty, Ramon Huerta |
2015
![]() Programmable probiotics for detection of cancer in urineTal Danino, Arthur Prindle, Gabriel A. Kwong, Matthew Skalak, Howard Li, Kaitlin Allen, Jeff Hasty, Sangeeta N. Bhatia |
![]() A Microfluidic Platform for Long-Term Monitoring of Algae in a Dynamic EnvironmentChung Sze Luke, Jangir Selimkhanov, Leo Baumgart, Susan E. Cohen, Susan S. Golden, Natalie A. Cookson, Jeff Hasty |
![]() Orthogonal Modular Gene Repression in E. coli Using Engineered CRISPR/Cas9Andriy Didovyk, Bartlomiej Borek, Jeff Hasty, Lev Tsimring |
![]() Distributed Classifier Based on Genetically Engineered Bacterial Cell CulturesAndriy Didovyk, Oleg I. Kanakov, Mikhail V. Ivanchenko, Jeff Hasty, Ramon Huerta, Lev Tsimring |
2014
![]() Rapid and tunable post-translational coupling of genetic circuitsArthur Prindle, Jangir Selimkhanov, Howard Li, Ivan Razinkov, Lev S. Tsimring, and Jeff HastyNature, 508: 387-391 (2014) Supplement |
![]() Accurate information transmission through dynamic biochemical signaling networksJangir Selimkhanov, Brooks Taylor, Jason Yao, Anna Pilko, John Albeck, Alexander Hoffmann, Lev Tsimring, Roy WollmanScience, 346: 1370-1373 (2014) |
![]() Synchronization of Degrade-and-Fire Oscillations via a Common ActivatorWilliam Mather, Jeff Hasty, and Lev S. TsimringPhysical Review Letters, 113, 128102 (2014) |
![]() In-Vivo Real-Time Control of Protein Expression from Endogenous and Synthetic Gene NetworksFilippo Menolascina, Gianfranco Fiore, Emanuele Orabona, Luca De Stefano, Mike Ferry, Jeff Hasty, Mario di Bernardo, Diego di Bernardo |
![]() Dynamic Localization of the Cyanobacterial Circadian Clock ProteinsSusan E. Cohen, Marcella L. Erb, Jangir Selimkhanov, Guogang Dong, Jeff Hasty, Joe Pogliano, Susan S. Golden |
2013
![]() Measuring Competitive Fitness in Dynamic EnvironmentsIvan A. Razinkov, Bridget L. Baumgartner, MR Bennett, Lev Tsimring, and Jeff Hasty |
![]() Dual Delayed Feedback Provides Sensitivity and Robustness to the NF-kB Signaling ModuleDiane M. Longo, Jangir Selimkhanov, Jeffrey D. Kearns, Jeff Hasty, Alexander Hoffmann, Lev S. TsimringPloS Computational Biology, 9(6): e1003112 (2013) |
![]() Measuring Growth and Gene Expression Dynamics of Tumor-Targeted S.Typhimurium BacteriaTal Danino, Arthur Prindle, Jeff Hasty, Sangeeta Bhatia |
![]() Translational Cross Talk in Gene NetworksWilliam H. Mather, Jeff Hasty, Lev S. Tsimring, and Ruth J. Williams |
2012
![]() A sensing array of radically coupled genetic ‘biopixels’Arthur Prindle, Phillip Samayoa, Ivan Razinkov, Tal Danino, Lev Tsimring, and Jeff Hasty |
![]() Making gene circuits singArthur Prindle and Jeff Hasty |
![]() In vivo gene expression dynamics of tumor-targeted bacteriaTal Danino, Justin Lo, Arthur Prindle, Jeff Hasty, and Sangeeta N. Bhatia |
![]() Recent advances in single-cell studies of gene regulationJangir Selimkhanov, Jeff Hasty, and Lev TsimringCurrent Opinion in Biotechnology, 23:34-40 (2012) |
![]() Vacuum-assisted cell loading enables shear-free mammalian microfluidic cultureMartin Kolnik, Lev Tsimring, and Jeff Hasty |
![]() Genetic circuits in Salmonella typhimuriumArthur Prindle, Jangir Selimkhanov, Tal Danino, Phillip Samayoa, Anna Goldberg, Sangeeta N. Bhatia, and Jeff Hasty |
![]() Fast stochastic algorithm for simulating evolutionary population dynamicsWilliam H. Mather, Jeff Hasty, and Lev S. TsimringBioinformatics, Vol. 28, No. 9 (2012) |
![]() Synthetic biology approaches to biofuel productionMichael S. Ferry, Jeff Hasty, Natalie A. CooksonBiofuels, Vol. 3, No. 1 (2012) |
2011
![]() Entrainment of a population of synthetic genetic oscillatorsOctavio Mondragon-Palomino, Tal Danino, Jangir Selimkhanov, Lev Tsimring, and Jeff Hasty |
![]() Queueing up for enzymatic processing: correlated signaling through coupled degradationNatalie A. Cookson, William H. Mather, Tal Danino, Octavio Mondragón-Palomino, Ruth J. Williams, Lev S. Tsimring and Jeff HastyMolecular Systems Biology, 16:21:00 (2011) |
![]() Antagonistic gene transcripts regulate adaptation to new growth environmentsBridget L. Baumgartner, Matthew R. Bennett, Michael Ferry, Tracy L. Johnson, Lev S. Tsimring, and Jeff Hasty |
![]() Yeast Dynamically Modify Their Environment to Achieve Better Mating EfficiencyMeng Jin, Beverly Errede, Marcelo Behar, Will Mather, Sujata Nayak, Jeff Hasty, Henrik G. Dohlman, and Timothy C. Elston |
![]() In-Silico Patterning of Vascular Mesenchymal Cells in Three DimensionsTal Danino, Dmitri Volfson, Sangeeta N. Bhatia, Lev Tsimring, Jeff Hasty |
![]() Microfluidics for synthetic biology: From design to executionMichael Ferry, Ivan Razinkov, and Jeff HastyMethods in Enzymology, 497: 295-372 (2011) |
![]() Buckling instability in ordered bacterial coloniesDenis Boyer, William Mather, Octavio Mondragon-Palomino, Sirio Orozco-Fuente, Tal Danino, Jeff Hasty, and Lev Tsimring |
![]() Factorized time-dependent distributions for certain multiclass queueing networks and an application to enzymatic processing networkWilliam H. Mather, Jeff Hasty, Lev S. Tsimring, and Ruth J. Williams |
2010
![]() A synchronized quorum of genetic clocksTal Danino, Octavio Mondragon-Palomino, Lev Tsimring, Jeff Hasty |
![]() Streaming Instability in Growing Cell PopulationsWilliam Mather, Octavio Mondragon-Palomino, Tal Danino, Jeff Hasty, and Lev S. Tsimring |
![]() Correlation Resonance Generated by Coupled Enzymatic ProcessingWilliam H. Mather, Natalie A. Cookson, Jeff Hasty, Lev S. Tsimring, and Ruth J. Wiliams |
![]() |
![]() Circadian rhythms in Neurospora crassa: Dynamics of the clock component frequency visualized using a fluorescent reporterErnestina Castro-Longoria, Michael Ferry, Salomon Bartnicki-Garcia, Jeff Hasty, Stuart BrodyFungal Genetics and Biology, 47: 332-341 (2010) |
![]() Phenotypic impact of regulatory noise in cellular stress-response pathwaysDaniil Zhuravel, Dawn Fraser, Simon St-Pierre, Lioudmila Tepliakova, Wyming L. Pang, Jeff Hasty, Mads KaernSystems and Synthetic Biology, 4(2): 105-116 (2010) |
2009
![]() Microfluidic devices for measuring gene network dynamics in single cellsMatthew Bennett, Jeff HastyNature Reviews Genetics, 10(9): 628-38 (2009) |
![]() Overpowering the component problemMatthew Bennett, Jeff HastyNature Biotechnology, 27(5): 450-1 (2009) |
![]() Cell cycle-dependent variations in protein concentrationNatalie Cookson, Scott Cookson, Lev Tsimring, Jeff HastyNucleic Acids Research, 38(8) (2009) |
![]() The pedestrian watchmaker: Genetic clocks from engineered oscillatorsNatalie Cookson, Lev Tsimring, Jeff HastyFEBS Letters, 583 3931_3937 (2009) |
![]() Coherent activation of a synthetic mammalian gene networkDiane Longo, Alexander Hoffman, Lev Tsimring, Jeff HastySystems and Synthetic Biology, DOI 10.1007/s11693-009-9044-5 (2009) |
![]() Delay-Induced Degrade-and-Fire Oscillations in Small Genetic CircuitsWilliam Mather, Matthew Bennett, Jeff Hasty, Lev TsimringPhysical Review Letters, 102(6):068105(4) (2009) |
2008
![]() Metabolic gene regulation in a dynamically changing environmentMatthew Bennett, Wyming Lee Pang, Natalie Ostroff, Bridget Baumgartner, Sujata Nayak, Lev Tsimring, Jeff Hasty |
![]() A fast, robust and tunable synthetic gene oscillatorJesse Stricker, Scott Cookson, Matthew Bennett, William Mather, Lev Tsimring, Jeff HastyNature, 456(7221):516-9 (2008) |
![]() |
![]() Athermal Dynamics of Strongly Coupled Stochastic Three-State OscillatorsBastien Fernandez, Lev TsimringPhysical Review Letters, 100(16):165705 (2008) |
![]() Regulation of Cell Signaling Dynamics by the Protein Kinase-Scaffold Ste5Nan Hao, Sujata Nayak, Marcelo Behar, Ryan Shanks, Michal Nagiec, Beverly Errede, Jeff Hasty, Timothy Elston, Henrik DohlmanMolecular Cell, 30(5):539-656 (2008) |
![]() A molecular noise generatorTing Lu, Michael Ferry, Ron Weiss, Jeff HastyPhysical Biology, 5(3):36006 (2008) |
![]() Biomechanical ordering of dense cell populationsDmitri Volfson, Scott Cookson, Jeff Hasty, Lev TsimringProceedings of the National Academy of Sciences, 105(40):15346-51 (2008) |
2007
![]() Transient dynamics of genetic regulatory networksMatthew Bennett, Dmitri Volfson, Lev Tsimring, Jeff HastyBiophysical Journal, 92: 3501-3512 (2007) |
![]() A DNA methylation-based switch generates bistable gene expressionMatthew Bennett, Jeff HastyNature Genetics, 39: 146-147 (2007) |
![]() A synthetic gene network for tuning protein degradation in Saccharomyces cerevisiaeChris Grilly, Jesse Stricker, Wyming Lee Pang, Matthew Bennett, Jeff HastyMolecular Systems Biology, msb4100168 (2007) |
![]() Phenotypic variability of growing cellular populationsTing Lu, Tongye Shen, Matthew Bennett, Peter Wolynes, Jeff HastyProceedings of the National Academy of Sciences, 104:18982_18987 (2007) |
2006
![]() A bottom-up approach to gene regulationNicholas Guido, Xiao Wang, David Adalsteinsson, David McMillen, Jeff Hasty, Charles Cantor, Timothy Elston, J.J. CollinsNature, 439: 856-860 (2006) |
![]() Dynamics of single-cell gene expressionDiane Longo, Jeff HastyMolecular Systems Biology, msb4100110 (2006) |
![]() Imaging gene expression: Tiny signals make a big noiseDiane Longo, Jeff HastyNature Chemical Biology, 2: 181-182 (2006) |
![]() Statistics of cellular signal transduction as a race to the nucleus by multiple random walkers in compartment/phosphorylation spaceTing Lu, Tongye Shen, Chenghang Zong, Jeff Hasty, Peter WolynesProceedings of the National Academy of Sciences, 103:16752-16757 (2006) |
![]() Effective temperature in stochastic kinetics and gene networksTing Lu, Jeff Hasty, Peter WolynesBiophysical Journal, 91: 84-94 (2006) |
![]() Stochastically driven genetic circuitsLev Tsimring, Dmitri Volfson, Jeff HastyChaos, 16: 026103 (2006) |
![]() Origins of extrinsic variability in eukaryotic gene expressionDmitri Volfson, Jennifer Marciniak, Natalie Ostroff, William Blake, Lev Tsimring, Jeff HastyNature, 439: 861-864 (2006) |
2005
![]() Delay-induced stochastic oscillations in gene regulationDmitri Bratsun, Dmitri Volfson, Lev Tsimring, Jeff HastyProceedings of the National Academy of Sciences, 102: 14593-14598 (2005) |
![]() Monitoring dynamics of single-cell gene expression over multiple cell cyclesScott Cookson, Natalie Ostroff, Wyming Lee Pang, Dmitri Volfson, Jeff HastyMolecular Systems Biology, msb4100032 (2005) |
2004
![]() Cellular growth and division in the Gillespie algorithmTing Lu, Dmitri Volfson, Lev Tsimring, Jeff HastyIEE Systems Biology, 1:121-127 (2004) |
2003
![]() Prediction and measurement of an autoregulatory genetic moduleFarren Isaacs, Jeff Hasty, Charles Cantor, J.J. CollinsProceedings of the National Academy of Sciences, 100 (13) 7714-7719 (2003) |
![]() Reverse engineering gene networks: Integrating genetic perturbations with dynamical modelingJesper Tegner, Stephen Yeung, Jeff Hasty, J.J. CollinsProceedings of the National Academy of Sciences, 100 (10): 5944-5949 (2003) |
2002
![]() A synthetic gene network for entraining and amplifying cellular oscillationsJeff Hasty, Milos Dolnik, Vivi Rottschafer, J.J. CollinsPhysical Review Letters, 88 (14): art. no. 148101 (2002) |
![]() Design then mutateJeff HastyProceedings of the National Academy of Sciences, 99 (26): 16516-16518 (2002) |
![]() |
![]() |
![]() Synchronizing genetic relaxation oscillators by intercell signallingDavid McMillen, Nancy Kopell, Jeff Hasty, J.J. CollinsProceedings of the National Academy of Sciences, 99 (2): 679-684 (2002) |
2001
![]() Designer gene networks: Towards fundamental cellular controlJeff Hasty, Farren Isaacs, Milos Dolnik, David McMillen, J.J. CollinsChaos, 11 (1): 207-220 (2001) |
![]() Computational studies of gene regulatory networks: in numero molecular biologyJeff Hasty, David McMillen, Farren Isaacs, J.J. CollinsNature Reviews Genetics, 2 (4): 268-279 (2001) |
![]() |
![]() Wavelets of excitibility in sensory neuronsJeff Hasty, J.J. Collins, Kurt Wiesenfeld, Peter GriggJournal of Neurophysiology, 86 (4): 2097-2101 (2001) |
![]() Complex ligand-protein systems: a globally convergent iterative method for the n x m caseJ Pradines, Jeff Hasty, K PakdamanJournal of Mathematical Biology, 43 (4): 313-324 (2001) |
2000
![]() Noise-based switches and amplifiers for gene expressionJeff Hasty, Joel Pradines, Milos Dolnik, J.J. CollinsProceedings of the National Academy of Sciences, 97 (5): 2075-2080 (2000) |
1998
![]() Renormalization group for directed sandpile modelsJeff Hasty, Kurt WiesenfeldPhysical Review Letters, 81 (8): 1722-1725 (1998) |
1997
![]() Renormalization of one-dimensional avalanche modelsJeff Hasty, Kurt WiesenfeldJournal of Statistical Physics, 86 (5-6): 11/79-1201 (1997) |















































