Drawing from a theoretical Physics background, my postdoc has primarily focused on the theoretical analysis of protein interaction networks and gene circuits. I am especially interested in the study of nonlinear response characteristics and delayed interactions in the context of stochastic models. A recurring theme in this research is the development of design principles for synthetic networks. I have also gained some experience with the design and implementation microfluidic devices, culminating in the synthesis of a device that applies a spatiotemporal signal across a bed of cells.
(submitted) Mather, W.H., Hasty, J., Tsimring, L.S. Fast stochastic algorithm for simulating evolutionary population dynamics.
 Cookson, N.A.*, Mather, W.H.*, Danino, T., Mondragon-Palomino, O., Williams, R.J., Tsimring, L.S., and Hasty, J. Queueing up for enzymatic processing: Correlated signaling through coupled degradation. Molecular Systems Biology 7, a. 561 (2011).
 Jin, M., Errede, B., Behar, M., Mather, W.H., Nayak, S., Hasty, J., Dohlman, H.G., and Elston, T.C. Yeast dynamically modify their environment to achieve better mating efficiency. Science Signaling 4, ra54 (2011).
 Mather, W.H., Hasty, J., Tsimring, L.S., Williams, R.J. Factorized time-dependent distributions for certain multiclass queueing networks and an application to enzymatic processing networks. Queueing Systems 69, 313-328 (2011).
 Boyer D.*, Mather W.H.*, Mondragn-Palomino O.,
Orozco-Fuentes S., Danino T., Hasty J, Tsimring L.S. Buckling
instability in ordered bacterial colonies. Physical Biology 8, 026008
 Mather, W.H., Cookson, N.A., Hasty, J.,
Tsimring, L.S., Williams, R.J. Correlation Resonance Generated by
Coupled Enzymatic Processing. Biophysical Journal 99, 3172–3181 (2010).
 Mather, W.H., Mondragon-Palomino, O. Danino, T.,
Hasty, J., Tsimring, L.S. Streaming Instability in Growing Cell
Populations. Physical Review Letters 104, 208101 (2010).
 Mather, W., Bennett, M. R., Hasty, J. & Tsimring, L. S. Delay-induced degrade-and-fire oscillations in small genetic circuits. Physical Review Letters 102, 068105 (2009).
 Stricker, J. et al. A fast, robust and tunable synthetic gene oscillator. Nature 456, 516–519 (2008).
 Mather, W. H. & Fox, R. F. Kinesin’s biased stepping mechanism: Amplification of neck linker zippering. Biophysical Journal 91, 2416–2426 (2006).
 Mather, W. H. & Fox, R. F. Universal turning point behavior for Gaussian-Klauder states and an application for maximally eccentric Rydberg atoms. Physical Review A 74 (2006).
 Mather, W. H. & Fox, R. F. Coherent-state
analysis of the quantum bouncing ball. Physical Review A 73 (2006).
Thesis: Mather, W. Rectiﬁed Brownian Motion in
Biology. Ph.D. thesis. Georgia Institute of Technology (2003).
E-Book reference: Some work on polymer models found
in Mysterium Tremendum Part 3: