Systems Biodynamics Lab
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Matt Bennett
Postdoctoral Fellow
NIH Kirschstein Fellow

Email: mbennett AT ucsd.edu
Phone: 858.822.3857
My CV.

Education

Ph.D., Physics, Georgia Tech (2006)
B.S., Physics, Georgia Tech (2000)


Research Interests

My research interests generally lie in the field of nonlinear dynamics, with particular emphasis on synchronization, stochastic processes and non-equilibrium statistical physics. Currently I am working to model various genetic networks. These networks involve complex dynamical interactions between genes and the proteins they produce. For instance, as growing cells are exposed to fluctuating carbon sources, the regulatory pathways that code for transport transduce the environmental signals in different ways. It is one of the goals of my research to understand how these pathways react to different signals, and how the production of regulatory proteins is subsequently affected.

Publications

  1. A. Handel and M. R. Bennett, “Surviving the bottleneck: Transmission mutants and the evolution of microbial populations,” Submitted to Evolution (2008).
  2. J. Stricker, S. Cookson, M. R. Bennett, L. S. Tsimring and J. Hasty, “A robust and tunable synthetic gene oscillator,” Submitted to Nature (2008).
  3. M. R. Bennett, W. L. Pang, N. A. Ostroff, L. S. Tsimring and J. Hasty, “Metabolic gene regulation in a dynamically changing environment,” Accepted for publication in Nature (2008).
  4. M. R. Bennett and J. Hasty, “Genome rewired,” Nature 452, 824-825 (2008). [PDF]
  5. T. Lu, T. Shen, M. R. Bennett, P. G. Wolynes and J. Hasty, “Phenotypic variability of growing cellular populations,” Proc. Natl. Acad. Sci. USA 104, 18982-18987 (2007). [PDF]
  6. C. Grilly, J. Stricker, W. L. Pang, M. R. Bennett and J. Hasty, “A synthetic gene network for tuning protein degradation in Saccharomyces cerevisiae,” Mol. Sys. Bio. 3, 127 (2007). [PDF]
  7. M. R. Bennett, D. Volfson, L. Tsimring and J. Hasty, “Transient dynamics of genetic regulatory networks,” Biophys. J. 92, 3501-3512 (2007). [PDF]
  8. M. R. Bennett and J. Hasty, “A DNA methylation-based switch generates bistable gene expression,” Nat. Genet. (News and Views) 39, 146-147 (2007). [PDF]
  9. M. R. Bennett and K. Wiesenfeld, “Towards a unified rate theory of stochastic resonance,” Fluct. Noise Lett. 6, L405-L413 (2006). [Preprint]
  10. M. R. Bennett, “Synchronization and Signal Enhancement in Nonlinear and Stochastic Systems,” Ph.D. Dissertation, Georgia Tech (2006). [PDF]
  11. J. F. Lindner, M. Bennett and K. Wiesenfeld, “Potential energy landscape and finite-state models of array-enhanced stochastic resonance,” Phys. Rev. E 73, 031107 (2006). [PDF]
  12. J. F. Lindner, M. Bennett and K. Wiesenfeld, “Stochastic resonance in the mechanoelectrical transduction of hair cells,” Phys. Rev. E 72, 051911 (2005) and Virtual Journal of Biological Physics Research 10, no. 10 (2005). [PDF]
  13. M. Bennett, K. Wiesenfeld and F. Jaramillo, “Stochastic resonance in hair cells,” Fluct. Noise Lett. 4, L1-L10 (2004). [PDF]
  14. M. Bennett and K. Wiesenfeld, “Averaged equations for distributed Josephson junction arrays,” Physica D 192, 196-214 (2004). [Preprint]
  15. M. Bennett, M. F. Schatz, H. Rockwood and K. Wiesenfeld, “Huygens’ clocks,” Proc. Roy. Soc. London A 458, 563-579 (2002). [PDF]