Wyming Lee Pang
Graduate Student
Ph.D., Bioengineering, University of California, San Diego, (In Progress)
M.S., Bioengineering, University of California, San Diego, 2003
B.S., Chemical Engineering, University of California, Davis, 2000
Email: wpang AT ucsd.edu
Phone: 858.822.3858
Biography/Research Profile:
I am interested in the study of biological functions under physiologically natural
microenvironments. This includes research in elucidating the details of cellular
communication, cellular population control and dynamics, the utilization of
systems based approaches to predicting cellular fates, and the mechanisms of
disease. Because work in these areas requires precise spatio-temporal control
of the cellular microenvironment, I am equally interested in the development
of microfluidic technologies specific to biological and medical applications.
For my doctoral work, I am using a device that combines the TµC with
a microfluidic waveform generation platform to study how gene regulatory networks
and their phenotypic characteristics respond to highly dynamic environmental
change. At the moment, I am studying the response of the galactose utilization
system in budding yeast (S. cerevisiae) to high frequency glucose perturbations.
I am also working on a microfluidic platform for the study of information
in glial communication networks in collaboration with the
Silva Research Group.
I have been working closely with one of Dr. Silva's graduate students, Diana
Yu, who provides expertise in the preparation, culture, and imaging of the
cell lines used. Together we have developed a device that traps a small population
(~10-20) of cells within a constantly perfused microchamber for observation.
