Biodynamics Lab

Our focus is on the development of an engineering-based methodology in the theoretical design and experimental construction of synthetic gene regulatory networks.

Mailing Address Department of Bioengineering || University of California, San Diego || Mailcode 0412 || 9500 Gilman Dr. || La Jolla, CA 92093-0412 || Phone:(858)822-3858 || Fax:(858)534-5722
Site created & maintained by Martin Kolnik & Tal Danino

Dynamics in Systems Biology

Our research is focused on the construction and utilization of synthetic
gene circuits for dissecting, analyzing, and controlling the dynamical interactions involved in gene regulation. We combine tools from nonlinear dynamics and statistical physics with the extensive array of techniques in traditional molecular biology and microfluidic technology development. The power of this approach is that it can be used to study simplified systems in order to gain insight into
the modular components of gene regulation.

Funding:

National Insitutes of Health: National Institute of General Medical Sciences

National Science Foundation: Division of Bioengineering

National Science Foundation: Division of Cellular and Molecular Biology

	Systems Biology: genome rewired, NATURE
	Phenotypic variability of growing cellular populations, PNAS
	A synthetic gene network for tuning protein degradation in Saccharomyces cerevisiae, MSB
	Transient dynamics of genetic regulatory networks, BIOPHYS. J.
	Statistics of cellular signal transduction..., PNAS
	Stochastically driven genetic circuits, CHAOS
	[See complete list]